EEF1D antibody

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935106861
info@markelab.com
name
EEF1D antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02647
tested applications
ELISA, WB, IHC, IF

Description

Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.


Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements(HSE).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
eukaryotic translation elongation factor 1 delta(guanine nucleotide exchange protein) (EEF1D)
Host
Mouse
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000; IF: 1:10-1:100; IHC: 1:50-1:500
Clonality
monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Clone ID
6D9
Observed MW
40 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Protein A+G purification
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P29692
Gene ID
1936
Alias
Elongation factor 1-delta (EF-1-delta),Antigen NY-CO-4,EEF1D,EF1D
Background
Antibody anti-EEF1D
Status
RUO
Note
Mol. Weight 40 kDa

Descripción

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FNab02646

EEF1D antibody

This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.

Ver Producto
FNab02647

EEF1D antibody

Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements(HSE).

Ver Producto
FNab02648

EEF1D antibody

Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements(HSE).

Ver Producto