DYNC1I2 antibody
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Description
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component(p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | dynein, cytoplasmic 1, intermediate chain 2 (DYNC1I2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 68 kDa and 72 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13409 |
| Gene ID | 1781 |
| Alias | Cytoplasmic dynein 1 intermediate chain 2,Cytoplasmic dynein intermediate chain 2,Dynein intermediate chain 2, cytosolic (DH IC-2),DYNC1I2,DNCI2,DNCIC2 |
| Background | Antibody anti-DYNC1I2 |
| Status | RUO |
| Note | Mol. Weight 68 kDa and 72 kDa |
Descripción
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