DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway(By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
Primary Antibodies
polyclonal
human,mouse,rat
docking protein 4
Rabbit
IgG
Unconjugated
liquid
ELISA, IHC
37 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
IHC: 1:20-1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
DOK4
Downstream of tyrosine kinase 4,Insulin receptor substrate 5,IRS-5,IRS5
This product is for research use only.
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly o...
Precio a consultar
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