DOCK3 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
DOCK3 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab02494
Tested Applications
ELISA, WB
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | dedicator of cytokinesis 3 (DOCK3) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 233 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8IZD9 |
| Alias | DOCK3, MOCA, PBP, Dock3, dedicator of cytokinesis 3, NEDIDHA |
| Background | Antibody anti-DOCK3 |
| Status | RUO |
| Note | Mol. Weight 233 kDa |
Background
DOCK3, or MOCA, is a neuron-specific GEF for Rac1 that regulates neurite outgrowth, axonal growth, and synaptic plasticity in the CNS. It mediates actin rearrangement, promoting axonal guidance and dendritic remodeling. Highly expressed in neurons, DOCK3 maintains synapse connectivity and supports neuroprotection. Dysregulation contributes to neurodegenerative diseases like Alzheimer’s, where it influences tau phosphorylation and cell survival pathways such as ERK/Akt activation. DOCK3 deficiency causes motor and cognitive impairments in mouse models, highlighting its role in neuronal development, CNS recovery, and axonal regeneration.
Productos relacionados
Dedicator of Cytokinesis 3 (DOCK3) Antibody
Dedicator Of Cytokinesis 3 Antibody is a Rabbit Polyclonal antibody against Dedicator Of Cytokinesis 3.…
Ver producto
Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit
Human Dedicator Of Cytokinesis 3 (DOCK3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human De…
Ver producto