DNMT3L antibody
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Description
Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4(H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DNA(cytosine-5-)-methyltransferase 3-like (DNMT3L) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 44kd and 70kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UJW3 |
| Gene ID | 29947 |
| Alias | DNA (cytosine-5)-methyltransferase 3-like,DNMT3L |
| Background | Antibody anti-DNMT3L |
| Status | RUO |
| Note | Mol. Weight 44 kD and 70kd |
Descripción
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DNMT3L antibody
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