DNM2 antibody
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Description
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones(By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis(PubMed:12498685). Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | dynamin 2 (DNM2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 100kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P50570 |
| Gene ID | 1785 |
| Alias | Dynamin-2,Dynamin 2,Dynamin II,DNM2,DYN2 |
| Background | Antibody anti-DNM2 |
| Status | RUO |
| Note | Mol. Weight 100 kDa |
Descripción
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Human DNM2 (Dynamin-2) ELISA Kit
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DNM2 antibody
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones(By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis(PubMed:12498685). Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane(By similarity).
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Dynamin-2 (DNM2) Antibody
DNM2 Antibody is a Rabbit Polyclonal antibody against DNM2. Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.
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