DNAJA1 antibody
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935106861
info@markelab.com
name
DNAJA1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02439
tested applications
ELISA, WB, IHC
Description
Co-chaperone for HSPA8/Hsc70(PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A(in vitro)(PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis(PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV(PubMed:24512202).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DnaJ(Hsp40) homolog, subfamily A, member 1 (DNAJA1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P31689 |
| Gene ID | 3301 |
| Alias | DnaJ homolog subfamily A member 1,DnaJ protein homolog 2,HSDJ,Heat shock 40 kDa protein 4,Heat shock protein J2 (HSJ-2),Human DnaJ protein 2 (hDj-2),DNAJA1,DNAJ2,HDJ2,HSJ2,HSPF4 |
| Background | Antibody anti-DNAJA1 |
| Status | RUO |
| Note | Mol. Weight 45 kDa |
Descripción
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DNAJA1 antibody
Co-chaperone for HSPA8/Hsc70(PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A(in vitro)(PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis(PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV(PubMed:24512202).
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