DHRS2 antibody
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Description
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | dehydrogenase/reductase(SDR family) member 2 (DHRS2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13268 |
| Gene ID | 10202 |
| Alias | Dehydrogenase/reductase SDR family member 2, mitochondrial,Dicarbonyl reductase HEP27,Protein D,Short chain dehydrogenase/reductase family 25C member 1 (Protein SDR25C1),DHRS2,SDR25C1 |
| Background | Antibody anti-DHRS2 |
| Status | RUO |
| Note | Mol. Weight 30 kDa |
Descripción
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