DGAT1 antibody

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935106861
info@markelab.com
name
DGAT1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02349
tested applications
ELISA, WB, IHC, IP

Description

Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL(very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase(ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
diacylglycerol O-acyltransferase homolog 1(Mouse) (DGAT1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
55 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O75907
Gene ID
8694
Alias
Diacylglycerol O-acyltransferase 1,ACAT-related gene product 1,Acyl-CoA retinol O-fatty-acyltransferase (ARAT, Retinol O-fatty-acyltransferase),Diglyceride acyltransferase,DGAT1,AGRP1,DGAT
Background
Antibody anti-DGAT1
Status
RUO
Note
Mol. Weight 55 kDa

Descripción

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FNab02349

DGAT1 antibody

Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL(very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase(ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.

Ver Producto