DEF6 antibody
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Description
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor(GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2(T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | differentially expressed in FDCP 6 homolog(Mouse) (DEF6) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 74 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H4E7 |
| Gene ID | 50619 |
| Alias | Differentially expressed in FDCP 6 homolog (DEF-6),IRF4-binding protein,DEF6,IBP |
| Background | Antibody anti-DEF6 |
| Status | RUO |
| Note | Mol. Weight 74 kDa |
Descripción
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