CYP51A1 antibody
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Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51A1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 63 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q16850 |
| Gene ID | 1595 |
| Alias | Lanosterol 14-alpha demethylase (LDM),CYPLI,Cytochrome P450 51A1 (CYP51A1),Cytochrome P450-14DM (Cytochrome P45014DM),Cytochrome P450LI,Sterol 14-alpha demethylase,CYP51A1,CYP51 |
| Background | Antibody anti-CYP51A1 |
| Status | RUO |
| Note | Mol. Weight 63 kDa |
Descripción
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