CUX1 antibody
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Description
Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions(MARs)(5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor(TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | cut-like homeobox 1 (CUX1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:3000; IP:1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 80 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P39880 |
| Gene ID | 1523 |
| Alias | Homeobox protein cut-like 1,CCAAT displacement protein (CDP),CDP/Cux p200,Homeobox protein cux-1,CDP/Cux p110,CUX1,CUTL1 |
| Background | Antibody anti-CUX1 |
| Status | RUO |
| Note | Mol. Weight 80 kDa |
Descripción
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