CTBP2 antibody

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935106861
info@markelab.com
name
CTBP2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02047
tested applications
ELISA, WB, IHC, IP

Description

Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue(BAT) differentiation(By similarity). 


Isoform 2 probably acts as a scaffold for specialized synapses.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
C-terminal binding protein 2 (CTBP2)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
49 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P56545
Gene ID
1488
Alias
C-terminal-binding protein 2 (CtBP2),CTBP2
Background
Antibody anti-CTBP2
Status
RUO
Note
Mol. Weight 49 kDa

Descripción

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C-Terminal-Binding Protein 2 (CTBP2) Antibody

CTBP2 Antibody is a Rabbit Polyclonal antibody against CTBP2. This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.

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