CTTN antibody

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935106861
info@markelab.com
name
CTTN antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01886
tested applications
ELISA, WB, IHC, FC, IF, IP

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
cortactin (CTTN)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
75~80 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, FC, IF, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q14247
Alias
Src substrate cortactin,Amplaxin,Oncogene EMS1,CTTN,EMS1
Background
Antibody anti-CTTN
Status
RUO
Note
Mol. Weight 75~80 kDa

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Cortactin (CTTN) Antibody

CTTN Antibody is a Rabbit Polyclonal antibody against CTTN. This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: regulating the interactions between components of adherens-type junctions and organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

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