COMMD5 antibody
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935106861
info@markelab.com
name
COMMD5 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01851
tested applications
ELISA, WB, IP
Description
May modulate activity of cullin-RING E3 ubiquitin ligase(CRL) complexes(PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis(By similarity). Down-regulates activation of NF-kappa-B(PubMed:15799966).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | COMM domain containing 5 (COMMD5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 25-28 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9GZQ3 |
| Gene ID | 54951 |
| Alias | COMM domain-containing protein 5,Hypertension-related calcium-regulated gene protein (HCaRG),COMMD5 |
| Background | Antibody anti-COMMD5 |
| Status | RUO |
| Note | Mol. Weight 25-28 kDa |
Descripción
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