CIT antibody
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Description
Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | citron(rho-interacting, serine/threonine kinase 21) (CIT) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 230kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O14578 |
| Gene ID | 11113 |
| Alias | Citron Rho-interacting kinase (CRIK),Serine/threonine-protein kinase 21,CIT,CRIK,KIAA0949,STK21 |
| Background | Antibody anti-CIT |
| Status | RUO |
| Note | Mol. Weight 230 kDa |
Descripción
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CIT antibody
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