CISD2 antibody
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935106861
info@markelab.com
name
CISD2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01718
tested applications
ELISA, WB, IHC, IF, IP
Description
Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CDGSH iron sulfur domain 2 (CISD2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 13-15 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N5K1 |
| Gene ID | 493856 |
| Alias | CDGSH iron-sulfur domain-containing protein 2,Endoplasmic reticulum intermembrane small protein,MitoNEET-related 1 protein (Miner1),Nutrient-deprivation autophagy factor-1 (NAF-1),CISD2,CDGSH2,ERIS,ZCD2 |
| Background | Antibody anti-CISD2 |
| Status | RUO |
| Note | Mol. Weight 13-15 kDa |
Descripción
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CISD2 antibody
Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
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