CHST15 antibody
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Description
Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate(PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | carbohydrate(N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 (CHST15) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 49 kDa, 69 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q7LFX5 |
| Gene ID | 51363 |
| Alias | Carbohydrate sulfotransferase 15,B-cell RAG-associated gene protein (hBRAG),N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (GalNAc4S-6ST),CHST15,BRAG,GALNAC4S6ST,KIAA0598 |
| Background | Antibody anti-CHST15 |
| Status | RUO |
| Note | Mol. Weight 49 kDa, 69 kDa |
Descripción
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CHST15 antibody
Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate(PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.
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