Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane(By similarity).
Primary Antibodies
polyclonal
human,mouse
cell adhesion molecule with homology to L1CAM(close homolog of L1)
Rabbit
IgG
Unconjugated
liquid
ELISA, WB
135 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
CHL1
CALL
This product is for research use only.
Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticit...
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