CHAT antibody

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935106861
info@markelab.com
name
CHAT antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01632
tested applications
ELISA, WB, IHC, IP, IF

Description

Catalyzes the reversible synthesis of acetylcholine(ACh) from acetyl CoA and choline at cholinergic synapses.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
choline acetyltransferase (CHAT)
Host
Rabbit
Reactivity
Human, Rat, Mouse
Recommended Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:500
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
47-50, 66-70 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IP, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P28329
Gene ID
1103
Alias
Choline O-acetyltransferase (CHOACTase, ChAT, Choline acetylase),CHAT
Background
Antibody anti-CHAT
Status
RUO
Note
Mol. Weight 47-50, 66-70 kDa

Descripción

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This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

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FNab01632

CHAT antibody

Catalyzes the reversible synthesis of acetylcholine(ACh) from acetyl CoA and choline at cholinergic synapses.

Ver Producto