CES1 antibody
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935106861
info@markelab.com
name
CES1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01615
tested applications
ELISA, WB, IHC
Description
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | carboxylesterase 1 (monocyte/macrophage serine esterase 1) (CES1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 62 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P23141 |
| Gene ID | 1066 |
| Alias | Liver carboxylesterase 1,Acyl-coenzyme A:cholesterol acyltransferase (ACAT),Brain carboxylesterase hBr1,Carboxylesterase 1 (CE-1, hCE-1),Cholesteryl ester hydrolase (CEH),Cocaine carboxylesterase,Egasyn,HMSE,Methylumbelliferyl-acetate deacetylase 1,Monocyte/macrophage serine esterase,Retinyl ester hydrolase (REH),Serine esterase 1,Triacylglycerol hydrolase (TGH),CES1,CES2,SES1 |
| Background | Antibody anti-CES1 |
| Status | RUO |
| Note | Mol. Weight 62 kDa |
Descripción
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This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
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