ITGB3BP antibody

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935106861
info@markelab.com
name
ITGB3BP antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01595
tested applications
ELISA, WB, IHC, IF

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
integrin beta 3 binding protein(beta3-endonexin) (ITGB3BP)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
25 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q13352
Alias
Centromere protein R (CENP-R),Beta-3-endonexin,Integrin beta-3-binding protein,Nuclear receptor-interacting factor 3,ITGB3BP,CENPR,NRIF3
Background
Antibody anti-ITGB3BP
Status
RUO
Note
Mol. Weight 25 kDa

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ITGB3BP Antibody is a Rabbit Polyclonal antibody against ITGB3BP. This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

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