CDCP1 antibody
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935106861
info@markelab.com
name
CDCP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01545
tested applications
ELISA, WB
Description
May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CUB domain containing protein 1 (CDCP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 130 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H5V8 |
| Gene ID | 64866 |
| Alias | Membrane glycoprotein gp140,CD318,TRASK,SIMA135,Subtractive immunization M plus HEp3-associated 135 kDa protein |
| Background | Antibody anti-CDCP1 |
| Status | RUO |
| Note | Mol. Weight 130 kDa |
Descripción
CDCP1 (CUB Domain Containing Protein 1), also known as CD318 or Trask, is a transmembrane protein widely expressed across cell types, including epithelial cells, stem cells, and notably in certain types of cancer cells. CDCP1 is known for its involvement in various cellular processes, including cell adhesion, migration, and signal transduction. It is a single-pass membrane protein characterized by extracellular CUB domains, which are implicated in protein-protein interactions, especially in cell communication and adhesion mechanisms. CDCP1 plays a crucial role in cancer biology, as its overexpression or aberrant activation has been observed in multiple malignancies, such as lung, colon, and breast cancer, where it contributes to processes like invasion, metastasis, and resistance to apoptosis. This makes CDCP1 an important molecule in cancer progression and a potential target for therapeutic interventions. Moreover, CDCP1 is implicated in non-cancerous biological pathways, including wound healing and tissue remodeling, which involve dynamic changes in cell adhesion and migration.
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CDCP1 antibody
May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Ver Producto