CDCA8 antibody
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935106861
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name
CDCA8 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01544
tested applications
ELISA, WB, IHC
Description
Component of the chromosomal passenger complex(CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | cell division cycle associated 8 (CDCA8) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 38-40 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q53HL2 |
| Gene ID | 55143 |
| Alias | Borealin,Cell division cycle-associated protein 8,Dasra-B (hDasra-B),Pluripotent embryonic stem cell-related gene 3 protein,CDCA8,PESCRG3 |
| Background | Antibody anti-CDCA8 |
| Status | RUO |
| Note | Mol. Weight 38-40 kDa |
Descripción
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CDCA8 antibody
Component of the chromosomal passenger complex(CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.
Ver Producto