CDC42EP2 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CDC42 effector protein(Rho GTPase binding) 2 (CDC42EP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 22kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O14613 |
| Gene ID | 10435 |
| Alias | Cdc42 effector protein 2,Binder of Rho GTPases 1,CDC42EP2,BORG1,CEP2 |
| Background | Antibody anti-CDC42EP2 |
| Status | RUO |
| Note | Mol. Weight 22 kDa |
Descripción
Related Products
CDC42EP2 antibody
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Ver Producto
CDC42 Effector Protein 2 (CDC42EP2) Antibody
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.
Ver Producto
CDC42 Effector Protein 2 (CDC42EP2) Antibody
Cdc42 Effector Protein (Rho Gtpase Binding) 2 Antibody is a Rabbit Polyclonal antibody against Cdc42 Effector Protein (Rho Gtpase Binding) 2.
Ver Producto