CD3E antibody

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935106861
info@markelab.com
name
CD3E antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01459
tested applications
ELISA, WB, IHC, IF, FC
Description
CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | CD3e molecule, epsilon (CD3-TCR complex) (CD3E) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | WB: 1:2000 - 1:20000; IHC: 1:1000 - 1:10000; IF: 1:50 - 500 |
Clonality | monoclonal |
Conjugation | Unconjugated |
Isotype | IgG1 |
Clone ID | 2E4 |
Observed MW | 23 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Protein A+G purification |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF, FC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | P07766 |
Gene ID | 916 |
Alias | T3E,TCRE,IMD18,CD3epsilon,T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain |
Background | Antibody anti-CD3E |
Status | RUO |
Note | Mol. Weight 23 kDa |
Descripción
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