anti- CD24 antibody

Este producto es parte de CD24 - CD24 molecule
anti- CD24 antibody

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935106861

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Precio

Precio a consultar

Antibody anti-CD24

proveedor

FineTest

reference

FNab01449

Tested Applications

ELISA, WB

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.


Background

CD24 is a small, heavily glycosylated cell surface protein that plays a crucial role in modulating immune responses, cell adhesion, and signal transduction. It is expressed in a wide range of tissues, including hematopoietic cells, neurons, epithelial cells, and cancer cells. CD24 has gained significant attention for its role in the immune system and its involvement in cancer biology. It has been implicated in both autoimmune diseases and tumor progression, making it an important molecule for understanding various pathophysiological processes. CD24 is involved in modulating immune responses, particularly in the context of inflammation, tumor immunology, and autoimmunity. It acts as a key regulator of innate immunity by interacting with various receptors, such as Siglec-10 on macrophages, to dampen inflammatory responses and promote immune tolerance. In the tumor microenvironment, CD24 can contribute to the immune evasion of cancer cells, allowing them to escape destruction by the immune system.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

CD24 molecule


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB


observerd MW

30-70 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500-1:2000


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

CD24


alias

CD24A,Signal transducer CD24,Small cell lung carcinoma cluster 4 antigen


note

This product is for research use only.


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