CD2 antibody

Este producto es parte de CD2 molecule
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935106861
info@markelab.com
name
CD2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01439
tested applications
ELISA, WB

Description

CD2 interacts with lymphocyte function-associated antigen(LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
CD2 molecule (CD2)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 1:500-1:2000
Clonality
monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Clone ID
8D6
Observed MW
55 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Protein A+G purification
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P06729
Gene ID
914
Alias
T11,SRBC,Erythrocyte receptor,LFA-2,LFA-3 receptor,Rosette receptor,T-cell surface antigen T11/Leu-5,T-cell surface antigen CD2
Background
Antibody anti-CD2
Status
RUO
Note
Mol. Weight 55 kDa

Descripción

The CD2 molecule, also known as T-cell surface antigen T11/Leu-5, is a cell adhesion molecule found on the surface of T cells, natural killer (NK) cells, and thymocytes. CD2 is part of the immunoglobulin (Ig) superfamily and plays a crucial role in the immune response by facilitating cell-cell adhesion and signal transduction. It was one of the first T-cell markers identified and has been extensively studied due to its importance in T cell and NK cell functions.

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