CD2 antibody

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935106861
info@markelab.com
name
CD2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01438
tested applications
ELISA, IHC, WB
Description
CD2 interacts with lymphocyte function-associated antigen(LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | CD2 molecule (CD2)  | 
| Host | Rabbit  | 
| Reactivity | Human, Mouse, Rat  | 
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200  | 
| Clonality | polyclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG  | 
| Observed MW | 40-55 kDa  | 
| Purity | ≥95% as determined by SDS-PAGE  | 
| Purification | Immunogen affinity purified  | 
| Size 1 | 100µg  | 
| Form | liquid  | 
| Tested Applications | ELISA, IHC, WB  | 
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)  | 
| UniProt ID | P06729  | 
| Gene ID | 914  | 
| Alias | T11,SRBC,Erythrocyte receptor,LFA-2,LFA-3 receptor,Rosette receptor,T-cell surface antigen T11/Leu-5,T-cell surface antigen CD2  | 
| Background | Antibody anti-CD2  | 
| Status | RUO  | 
| Note | Mol. Weight 40-55 kDa  | 
Descripción
The CD2 molecule, also known as T-cell surface antigen T11/Leu-5, is a cell adhesion molecule found on the surface of T cells, natural killer (NK) cells, and thymocytes. CD2 is part of the immunoglobulin (Ig) superfamily and plays a crucial role in the immune response by facilitating cell-cell adhesion and signal transduction. It was one of the first T-cell markers identified and has been extensively studied due to its importance in T cell and NK cell functions.
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Ver Producto