CD2 antibody
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Name
CD2 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab01437
Tested Applications
ELISA, WB, FC, IHC
Description
CD2 interacts with lymphocyte function-associated antigen(LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | CD2 molecule (CD2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, FC, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P06729 |
| Gene ID | 914 |
| Alias | T11,SRBC,Erythrocyte receptor,LFA-2,LFA-3 receptor,Rosette receptor,T-cell surface antigen T11/Leu-5,T-cell surface antigen CD2 |
| Background | Antibody anti-CD2 |
| Status | RUO |
| Note | Mol. Weight 50 kDa |
Background
The CD2 molecule, also known as T-cell surface antigen T11/Leu-5, is a cell adhesion molecule found on the surface of T cells, natural killer (NK) cells, and thymocytes. CD2 is part of the immunoglobulin (Ig) superfamily and plays a crucial role in the immune response by facilitating cell-cell adhesion and signal transduction. It was one of the first T-cell markers identified and has been extensively studied due to its importance in T cell and NK cell functions.
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