proveedor
FineTestreference
FNab01426Tested Applications
ELISA, IHC, WB, IF, FCreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211).
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
CD14 molecule
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, IHC, WB, IF, FC
observerd MW
50-55 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:50-1:500
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
CD14
alias
CD14, CD14 molecule
uniprot id
https://www.uniprot.org/uniprotkb/P08571
gene id
https://www.ncbi.nlm.nih.gov/gene/929
note
This product is for research use only.
Quizá le pueda interesar
Bovine CD14(Monocyte differentiation antigen CD14) ELISA Kit
proveedor
FineTestreference
EB0149reactivity
bovinestatus
RUOPrecio a consultar
Ver másMouse CD14(Monocyte differentiation antigen CD14) ELISA Kit
proveedor
FineTestreference
EM0039reactivity
mousestatus
RUOPrecio a consultar
Ver másanti- CD14 antibody
proveedor
FineTestreference
FNab01426Tested Applications
ELISA, IHC, WB, IF, FCreactivity
human,mouse,ratstatus
RUOclonality
polyclonalCoreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric li...
Precio a consultar
Ver más