anti- CD138/Syndecan-1 antibody

Este producto es parte de SDC1 - syndecan 1
anti- CD138/Syndecan-1 antibody

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-SDC1

proveedor

FineTest

reference

FNab01423

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse

status

RUO

clonality

polyclonal

Descripción

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.


Background

Syndecan-1 (SDC1), a cell surface heparan sulfate proteoglycan, is encoded by the SDC1 gene and is part of the syndecan family, which includes four distinct proteoglycans (syndecans 1-4). These proteoglycans are integral to cell surface structure, functioning in cellular communication, adhesion, migration, and the regulation of growth factors. Syndecan-1 is expressed on various cell types, including epithelial cells, B cells, and plasma cells, where it plays crucial roles in cell-matrix interactions and intracellular signaling. Additionally, SDC1 is dynamically regulated in response to tissue injury and inflammation, underscoring its significance in wound healing, inflammation, and cancer progression.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse


immunogen target

syndecan 1


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IHC


observerd MW

32 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)


or code

SDC1


alias

SDC,CD138,SYND1


note

This product is for research use only.


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