CCNY antibody
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935106861
info@markelab.com
name
CCNY antibody
category
Primary Antibodies
provider
FineTest
reference
FNab01386
tested applications
ELISA, WB, IF, IP
Description
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | cyclin Y (CCNY) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 33-39 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8ND76 |
| Gene ID | 219771 |
| Alias | Cyclin-Y (Cyc-Y),Cyclin box protein 1,Cyclin fold protein 1,cyclin-X,CCNY,C10orf9,CBCP1,CFP1 |
| Background | Antibody anti-CCNY |
| Status | RUO |
| Note | Mol. Weight 33-39 kDa |
Descripción
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