cTnI antibody

cTnI antibody
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Name
cTnI antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab01273
Tested Applications
ELISA, WB, IHC

Description

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Documentos del producto

Instrucciones
Descargar
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
troponin I type 3 (cardiac) (cTnI)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
26 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
UniProt ID
P19429
Gene ID
7137
Alias
Troponin I, cardiac muscle,Cardiac troponin I,TNNI3,TNNC1
Background
Antibody anti-cTnI
Status
RUO
Note
Mol. Weight 26 kDa

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