BMPR2 antibody

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935106861
info@markelab.com
name
BMPR2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00923
tested applications
ELISA, WB, IP

Description

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
bone morphogenetic protein receptor, type II(serine/threonine kinase) (BMPR2)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
120kd,97kd
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q13873
Gene ID
659
Alias
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor, BMPR-2),Bone morphogenetic protein receptor type II (BMP type II receptor, BMPR-II),BMPR2,PPH1
Background
Antibody anti-BMPR2
Status
RUO
Note
Mol. Weight 120 kDa, 97 kDa

Descripción

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