BHLHA15 antibody
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Description
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | basic helix-loop-helix family, member a15 (BHLHA15) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:500-1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q7RTS1 |
| Gene ID | 168620 |
| Alias | Class A basic helix-loop-helix protein 15 (bHLHa15),Class B basic helix-loop-helix protein 8 (bHLHb8),Muscle, intestine and stomach expression 1 (MIST-1),BHLHA15,BHLHB8,MIST1 |
| Background | Antibody anti-BHLHA15 |
| Status | RUO |
| Note | Mol. Weight 30 kDa |
Descripción
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