BECN1 antibody

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935106861
info@markelab.com
name
BECN1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00860
tested applications
ELISA, IHC, WB,IF

Description

Beclin-1(BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
beclin 1, autophagy related (BECN1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
60 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC, WB,IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q14457
Gene ID
8678
Alias
Beclin-1,Coiled-coil myosin-like BCL2-interacting protein,Protein GT197,Beclin-1-C 35 kDa,Beclin-1-C 37 kDa,BECN1,GT197
Background
Antibody anti-BECN1
Status
RUO
Note
Mol. Weight 60 kDa

Descripción

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