ADGRB2-Specific antibody

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935106861
info@markelab.com
name
ADGRB2-Specific antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00791
tested applications
ELISA, IHC
Description
BAI2 belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. BAI2 might be involved in angiogenesis inhibition. This antibody is specific to BAI2.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | brain-specific angiogenesis inhibitor 2 (ADGRB2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | O60241 |
Alias | ADGRB2,BAI2 |
Background | Antibody anti-ADGRB2 |
Status | RUO |
Note | This product is for research use only. |
Descripción
ADGRB2, or BAI2, is another member of the adhesion GPCR family with prominent expression in the central nervous system and vascular endothelial cells. It is involved in modulating vascular stability and angiogenesis through interactions with extracellular matrix proteins and intracellular signaling pathways. ADGRB2 is implicated in maintaining the blood-brain barrier and regulating vascular integrity, particularly during stress or injury. It also contributes to neurodevelopmental processes by influencing synapse formation and neuronal connectivity. Mutations or dysregulation of ADGRB2 have been linked to vascular abnormalities and potential roles in neurodegenerative diseases. Its functional overlap and synergy with other members of the ADGRB family emphasize its role in maintaining vascular and neural homeostasis.
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