ADGRB2-Specific antibody

Este producto es parte de ADGRB - Adhesion G protein-coupled receptor B
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935106861
info@markelab.com
name
ADGRB2-Specific antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00791
tested applications
ELISA, IHC

Description

BAI2 belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. BAI2 might be involved in angiogenesis inhibition. This antibody is specific to BAI2.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
brain-specific angiogenesis inhibitor 2 (ADGRB2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O60241
Alias
ADGRB2,BAI2
Background
Antibody anti-ADGRB2
Status
RUO
Note
This product is for research use only.

Descripción

ADGRB2, or BAI2, is another member of the adhesion GPCR family with prominent expression in the central nervous system and vascular endothelial cells. It is involved in modulating vascular stability and angiogenesis through interactions with extracellular matrix proteins and intracellular signaling pathways. ADGRB2 is implicated in maintaining the blood-brain barrier and regulating vascular integrity, particularly during stress or injury. It also contributes to neurodevelopmental processes by influencing synapse formation and neuronal connectivity. Mutations or dysregulation of ADGRB2 have been linked to vascular abnormalities and potential roles in neurodegenerative diseases. Its functional overlap and synergy with other members of the ADGRB family emphasize its role in maintaining vascular and neural homeostasis.

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