B4GALT6 antibody
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Description
Required for the biosynthesis of glycosphingolipids.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 (B4GALT6) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45-60kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, IF, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UBX8 |
| Gene ID | 9331 |
| Alias | Beta-1,4-galactosyltransferase 6 (Beta-1,4-GalTase 6, Beta4Gal-T6, b4Gal-T6),Glucosylceramide beta-1,4-galactosyltransferase,Lactosylceramide synthase (LacCer synthase),UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6,UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase,UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6,B4GALT6 |
| Background | Antibody anti-B4GALT6 |
| Status | RUO |
| Note | Mol. Weight 45-60 kDa |
Descripción
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Recombinant Human B4GALT6
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Beta-1,4-Galactosyltransferase 6 (B4GALT6) Antibody
This gene is one of seven beta-1, 4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1, 4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis.
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