B4GALT4 antibody
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Description
Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4 (B4GALT4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O60513 |
| Gene ID | 8702 |
| Alias | Beta-1,4-galactosyltransferase 4 (Beta-1,4-GalTase 4, Beta4Gal-T4, b4Gal-T4),Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase,Lactotriaosylceramide beta-1,4-galactosyltransferase,N-acetyllactosamine synthase,Nal synthase,UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4,UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4,B4GALT4 |
| Background | Antibody anti-B4GALT4 |
| Status | RUO |
| Note | Mol. Weight 50 kDa |
Descripción
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This gene is one of seven beta-1, 4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1, 4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene.
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