B3GNT5 antibody
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Description
Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto-or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide(LacCer) and neolactotetraosylceramide(nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide(nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 (B3GNT5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 44kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BYG0 |
| Gene ID | 84002 |
| Alias | Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase,Lactotriaosylceramide synthase (Lc(3)Cer synthase, Lc3 synthase),UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5 (BGnT-5, Beta-1,3-Gn-T5, Beta-1,3-N-acetylglucosaminyltransferase 5, Beta3Gn-T5),B3GNT5 |
| Background | Antibody anti-B3GNT5 |
| Status | RUO |
| Note | Mol. Weight 44 kDa |
Descripción
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