ATP6V1E1 antibody

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935106861
info@markelab.com
name
ATP6V1E1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00722
tested applications
ELISA, WB, IHC, IP

Description

Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 (ATP6V1E1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
31 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P36543
Gene ID
529
Alias
V-type proton ATPase subunit E 1 (V-ATPase subunit E 1),V-ATPase 31 kDa subunit (p31),Vacuolar proton pump subunit E 1,ATP6V1E1,ATP6E,ATP6E2
Background
Antibody anti-ATP6V1E1
Status
RUO
Note
Mol. Weight 31 kDa

Descripción

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ATP6V1E1 Antibody is a Rabbit Polyclonal antibody against ATP6V1E1. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.

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