ATG4D antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATG4 autophagy related 4 homolog D (ATG4D) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 53 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q86TL0 |
| Gene ID | 84971 |
| Alias | Cysteine protease ATG4D,AUT-like 4 cysteine endopeptidase,Autophagy-related cysteine endopeptidase 4 (Autophagin-4),Autophagy-related protein 4 homolog D (HsAPG4D),Cysteine protease ATG4D, mitochondrial,ATG4D,APG4D,AUTL4 |
| Background | Antibody anti-ATG4D |
| Status | RUO |
| Note | Mol. Weight 53 kDa |
Descripción
Related Products
ATG4D antibody
Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
Ver Producto
Recombinant Human ATG4D
Ver Producto
Autophagy Related 4D Cysteine Peptidase (ATG4D) Antibody
ATG4D Antibody is a Rabbit Polyclonal Antibody against ATG4D.
Ver Producto