ATG4B antibody
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935106861
info@markelab.com
name
ATG4B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00674
tested applications
ELISA, WB, IHC, IP
Description
Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATG4 autophagy related 4 homolog B (ATG4B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 44 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y4P1 |
| Gene ID | 23192 |
| Alias | Cysteine protease ATG4B,AUT-like 1 cysteine endopeptidase,Autophagy-related cysteine endopeptidase 1 (Autophagin-1),Autophagy-related protein 4 homolog B (HsAPG4B, hAPG4B),ATG4B,APG4B,AUTL1,KIAA0943 |
| Background | Antibody anti-ATG4B |
| Status | RUO |
| Note | Mol. Weight 44 kDa |
Descripción
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