ATG12 antibody

Product Graph
Contáctenos para saber el precio

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
ATG12 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00666
tested applications
ELISA, WB, IHC, IP

Description

Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.

Documents del producto

Instrucciones
Descargar
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
ATG12 autophagy related 12 homolog (ATG12)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
48-50kd
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O94817
Gene ID
9140
Alias
Ubiquitin-like protein ATG12,Autophagy-related protein 12 (APG12-like),ATG12,APG12,APG12L
Background
Antibody anti-ATG12
Status
RUO
Note
Mol. Weight 48-50 kDa

Descripción

Related Products

EH2224

Human ATG12 (Ubiquitin-like protein ATG12) ELISA Kit

Ver Producto
ER1922

Rat ATG12 ( autophagy protein 12 ) ELISA Kit

Ver Producto
FNab00666

ATG12 antibody

Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.

Ver Producto