anti- ATF6B antibody

Name: anti- ATF6B antibody
Brand: FineTest
SKU: FNab00665
Availability: OnlineOnly

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-ATF6B

proveedor

FineTest

reference

FNab00665

Tested Applications

ELISA, WB, IHC, IF, IP

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resulting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody could recognize ATF6 beta (110kd) and its cleaved forms(60,80kd )(PMID: 11256944)

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

activating transcription factor 6 beta

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC, IF, IP

observerd MW

110 kDa, 60 kDa, 80 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:1000-1:4000; IP:1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

ATF6B

alias

CREBL1, G13

uniprot id

https://www.uniprot.org/uniprotkb/Q99941

gene id

https://www.ncbi.nlm.nih.gov/gene/1388

note

This product is for research use only.

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Human ATF6B( Activating transcription factor 6 beta) ELISA Kit

proveedor

FineTest

reference

EH6520

reactivity

human

status

RUO

Precio a consultar