ATF6B antibody
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935106861
info@markelab.com
name
ATF6B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00665
tested applications
ELISA, WB, IHC, IF, IP
Description
The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resulting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody could recognize ATF6 beta (110kd) and its cleaved forms(60,80kd )(PMID: 11256944)
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | activating transcription factor 6 beta (ATF6B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:4000; IP:1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 110 kDa, 60 kDa, 80 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q99941 |
| Gene ID | 1388 |
| Alias | Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta),Activating transcription factor 6 beta (ATF6-beta),Protein G13,cAMP response element-binding protein-related protein (Creb-rp),cAMP-responsive element-binding protein-like 1,Processed cyclic AMP-dependent transcription factor ATF-6 beta,ATF6B,CREBL1,G13 |
| Background | Antibody anti-ATF6B |
| Status | RUO |
| Note | Mol. Weight 110 kDa, 60 kDa, 80 kDa |
Descripción
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Human ATF6B ( Activating transcription factor 6 beta) ELISA Kit
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ATF6B antibody
The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resulting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody could recognize ATF6 beta (110kd) and its cleaved forms(60,80kd )(PMID: 11256944)
Ver Producto