ASPA antibody
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Description
Catalyzes the deacetylation of N-acetylaspartic acid(NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | aspartoacylase(Canavan disease) (ASPA) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000; IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 36 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P45381 |
| Gene ID | 443 |
| Alias | Aspartoacylase,Aminoacylase-2 (ACY-2),ASPA,ACY2,ASP |
| Background | Antibody anti-ASPA |
| Status | RUO |
| Note | Mol. Weight 36 kDa |
Descripción
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ASPA antibody
Catalyzes the deacetylation of N-acetylaspartic acid(NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids.
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ASPA Antibody is a Rabbit Polyclonal antibody against ASPA. This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene.
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