ASGR2 antibody

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935106861
info@markelab.com
name
ASGR2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00636
tested applications
ELISA, WB, IHC, IP
Description
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | asialoglycoprotein receptor 2 (ASGR2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 39 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IP |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P07307 |
Gene ID | 433 |
Alias | Asialoglycoprotein receptor 2 (ASGP-R 2, ASGPR 2),C-type lectin domain family 4 member H2,Hepatic lectin H2 (HL-2),ASGR2,CLEC4H2 |
Background | Antibody anti-ASGR2 |
Status | RUO |
Note | Mol. Weight 39 kDa |
Descripción
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ASGR2 antibody
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Ver Producto