anti- ART3 antibody

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Product specifications
Category | Primary Antibodies |
Immunogen Target | ADP-ribosyltransferase 3 |
Host | Rabbit |
Reactivity | human,mouse |
Recommended Dilution | WB: 1:500-1:1000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 44 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q13508 |
Gene ID | 419 |
Alias | ADP ribosyltransferase 3, ART3, Ecto ADP ribosyltransferase 3, Mono(ADP ribosyl)transferase 3, TMART |
Background | Antibody anti-ART3 |
Status | RUO |
Note | This product is for research use only. |
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Ecto-ADP-Ribosyltransferase 3 (ART3) Antibody
ADP-ribosylation is a reversible posttranslational modification used to regulate protein function. ADP-ribosyltransferases, such as ART3, transfer ADP-ribose from NAD+ to the target protein, and ADP-ribosylhydrolases (see PARG; MIM 603501) reverse the reaction (Glowacki et al., 2002 [PubMed 12070318]).
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Ecto-ADP-Ribosyltransferase 3 (ART3) Antibody
Mono-ADP-ribosylation involves the transfer of the ADP-ribose moiety from NAD+ to a specific amino acid in the target protein. The rodent mono-ADP-ribosyltransferase RT6 is a glycosylphosphatidylinositol (GPI) anchored membrane protein specifically expressed at the cell surface of rat and mouse T lymphocytes. The predicted 367-amino acid human ART3 protein has an estimated molecular mass of 41.5 kD and contains a hydrophobic peptide signal at its N terminus, 3 consensus motifs specific to enzymes catalyzing ADP-ribose transfer, a hydrophobic C-terminal sequence characteristic of a GPI-anchored protein, a novel motif repeated 3 times at its C terminus, and 1 potential glycosylation site.1 The ART3 and rodent RT6 proteins share 35% amino acid identity.
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