anti- ARRDC3 antibody

Descripción

Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors(PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation(PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2(PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes(PubMed:23208550).

Características del producto

clonality

polyclonal

reactivity

human

immunogen target

arrestin domain containing 3

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IF

observerd MW

46 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:1000; IF: 1:10-1:100

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

ARRDC3

alias

ARRDC3, arrestin domain containing 3, KIAA1376, TLIMP

uniprot id

https://www.uniprot.org/uniprotkb/Q96B67

gene id

https://www.ncbi.nlm.nih.gov/gene/57561

note

This product is for research use only.

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